Cigarette Smoking in Male Patients with Chronic Schizophrenia in a Chinese Population: Prevalence and Relationship to Clinical Phenotypes

by Xiang Yang Zhang, Jun Liang, Da Chun Chen, Mei Hong Xiu, Jincai He, Wei Cheng, Zhiwei Wu, Fu De Yang, Colin N. Haile, Hongqiang Sun, Lin Lu, Therese A. Kosten, Thomas R. Kosten

The high prevalence of smoking in schizophrenia of European [...]

Repression of Floral Meristem Fate Is Crucial in Shaping Tomato Inflorescence

by Johanna Thouet, Muriel Quinet, Stanley Lutts, Jean-Marie Kinet, Claire Périlleux

Tomato is an important crop and hence there is a great interest in understanding the genetic basis of its flowering. Several genes have been identified by [...]



Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region

by Brian Weiner, James Gomez, Thomas C. Victor, Robert M. Warren, Alexander Sloutsky, Bonnie B. Plikaytis, James E. Posey, Paul D. van Helden, Nicolass C. Gey van Pittius, Michael Koehrsen, Peter Sisk, Christian Stolte, Jared White, Sebastien Gagneux, [...]

A Rapid Subtractive Immunization Method to Prepare Discriminatory Monoclonal Antibodies for Food E. coli O157:H7 Contamination

by Min Jin, Jing Lang, Zhi-Qiang Shen, Zhao-Li Chen, Zhi-Gang Qiu, Xin-Wei Wang, Jun-Wen Li

To detect food E. coli O157:H7 contamination rapidly and accurately, it is essential to prepare high specific monoclonal antibodies (mAbs) against the [...]

Effects of Sorafenib on Intra-Tumoral Interstitial Fluid Pressure and Circulating Biomarkers in Patients with Refractory Sarcomas (NCI Protocol 6948)

by Chandrajit P. Raut, Yves Boucher, Dan G. Duda, Jeffrey A. Morgan, Richard Quek, Marek Ancukiewicz, Johanna Lahdenranta, J. Paul Eder, George D. Demetri, Rakesh K. Jain
Purpose Sorafenib is a multi-targeted tyrosine kinase inhibitor with therapeutic [...]



Effects of a Non-Conservative Sequence on the Properties of β-glucuronidase from Aspergillus terreus Li-20

by Yanli Liu, Jie Huangfu, Feng Qi, Imdad Kaleem, Wenwen E, Chun Li

We cloned the β-glucuronidase gene (AtGUS) from Aspergillus terreus Li-20 encoding 657 amino acids (aa), which can transform glycyrrhizin into glycyrrhetinic acid [...]

Plasma Cell-Free DNA Levels Are Elevated in Acute Puumala Hantavirus Infection

by Tuula K. Outinen, Taru Kuparinen, Juulia Jylhävä, Sonja Leppänen, Jukka Mustonen, Satu Mäkelä, Ilkka Pörsti, Jaana Syrjänen, Antti Vaheri, Mikko Hurme
Introduction Puumala hantavirus (PUUV) causes a hemorrhagic fever with renal syndrome [...]

Ameliorated ConA-Induced Hepatitis in the Absence of PKC-theta

by Xianfeng Fang, Ruiqing Wang, Jian Ma, Yan Ding, Weirong Shang, Zuoming Sun

Severe liver injury that occurs when immune cells mistakenly attack an individual’s own liver cells leads to autoimmune hepatitis. In mice, acute hepatitis can be [...]

The Inherited Blindness Protein AIPL1 Regulates the Ubiquitin-Like FAT10 Pathway

by John S. Bett, Naheed Kanuga, Emma Richet, Gunter Schmidtke, Marcus Groettrup, Michael E. Cheetham, Jacqueline van der Spuy

Mutations in AIPL1 cause the inherited blindness Leber congenital amaurosis (LCA). AIPL1 has previously been shown [...]

Single Nucleotide Polymorphism in Gene Encoding Transcription Factor Prep1 Is Associated with HIV-1-Associated Dementia

by Sebastiaan M. Bol, Thijs Booiman, Daniëlle van Manen, Evelien M. Bunnik, Ard I. van Sighem, Margit Sieberer, Brigitte Boeser-Nunnink, Frank de Wolf, Hanneke Schuitemaker, Peter Portegies, Neeltje A. Kootstra, Angélique B. van ‘t Wout
Background [...]