Multi-Cellular Rosettes in the Mouse Visceral Endoderm Facilitate the Ordered Migration of Anterior Visceral Endoderm Cells

by Georgios Trichas, Aaron M. Smith, Natalia White, Vivienne Wilkins, Tomoko Watanabe, Abigail Moore, Bradley Joyce, Jacintha Sugnaseelan, Tristan A. Rodriguez, David Kay, Ruth E. Baker, Philip K. Maini, Shankar Srinivas

The visceral endoderm [...]

Genome-Wide Analysis of the World’s Sheep Breeds Reveals High Levels of Historic Mixture and Strong Recent Selection

by James W. Kijas, Johannes A. Lenstra, Ben Hayes, Simon Boitard, Laercio R. Porto Neto, Magali San Cristobal, Bertrand Servin, Russell McCulloch, Vicki Whan, Kimberly Gietzen, Samuel Paiva, William Barendse, Elena Ciani, Herman Raadsma, John McEwan, [...]



Development and Function of Invariant Natural Killer T Cells Producing TH2- and TH17-Cytokines

by Hiroshi Watarai, Etsuko Sekine-Kondo, Tomokuni Shigeura, Yasutaka Motomura, Takuwa Yasuda, Rumi Satoh, Hisahiro Yoshida, Masato Kubo, Hiroshi Kawamoto, Haruhiko Koseki, Masaru Taniguchi

There is heterogeneity in invariant natural killer T [...]

Built-in Timer Delays Differentiation

by Liza [...]

Pulsed Feedback Defers Cellular Differentiation

by Joe H. Levine, Michelle E. Fontes, Jonathan Dworkin, Michael B. Elowitz

Environmental signals induce diverse cellular differentiation programs. In certain systems, cells defer differentiation for extended time periods after the signal [...]



Reconstructing Speech from Human Auditory Cortex

by Brian N. Pasley, Stephen V. David, Nima Mesgarani, Adeen Flinker, Shihab A. Shamma, Nathan E. Crone, Robert T. Knight, Edward F. Chang

How the human auditory system extracts perceptually relevant acoustic features of speech is unknown. To [...]

Desperately Seeking Stable 50-Year-Old Landscapes with Patches and Long, Wide Corridors

by Paul Beier, Andrew J. [...]

Stochastic Expression of the Interferon-β Gene

by Mingwei Zhao, Jiangwen Zhang, Hemali Phatnani, Stefanie Scheu, Tom Maniatis

Virus infection of mammalian cells induces the production of high levels of type I interferons (IFNα and β), cytokines that orchestrate antiviral innate and [...]

Restoration of Ailing Wetlands

by Oswald J. Schmitz

It is widely held that humankind’s destructive tendencies when exploiting natural resources leads to irreparable harm to the environment. Yet, this thinking runs counter to evidence that many ecological systems damaged by [...]

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

by Mar Carmena, Xavier Pinson, Melpi Platani, Zeina Salloum, Zhenjie Xu, Anthony Clark, Fiona MacIsaac, Hiromi Ogawa, Ulrike Eggert, David M. Glover, Vincent Archambault, William C. Earnshaw

The coordinated activities at centromeres of two [...]