Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets.
J Pineal Res. 2012 Jan 30;
Authors: Mühlbauer E, Albrecht E, Bazwinsky-Wutschke I, Peschke [...]
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Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy. Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion. Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells. Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells. Melatonin enhances thapsigargin-induced apoptosis through reactive oxygen species-mediated upregulation of CCAAT-enhancer-binding protein homologous protein in human renal cancer cells. Light-regulated melatonin biosynthesis in rice during the senescence process in detached leaves. Melatonin increases dendritogenesis in the hilus of hippocampal organotypic cultures. Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity. Melatonin promotes embryonic development and reduces reactive oxygen species in vitrified mouse 2-cell embryos. Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis. |
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